A comparison of the oximes HS-6 and HI-6 in the therapy of soman intoxication in rodents
β Scribed by Larry A. Kepner; Otto L. Wolthuis
- Book ID
- 118322786
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- English
- Weight
- 377 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0014-2999
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π SIMILAR VOLUMES
The cardiopulmonary effects of HI-6, together with atropine and soman, were studied in the rat. HI-6 is an effective antidote in acute poisoning with the nerve agent soman. The therapeutic efficiency of HI-6 is still unclear and cannot be explained entirely by the HI-6 reactivating ability of acetyl
## Abstract The structure of the bispyridinium oximes, toxogonin, HSβ3, HSβ6 and HIβ6, used as antidotes in organophosphorus poisoning, is confirmed by ^13^C NMR spectroscopy. The ^13^C NMR spectra of the corresponding monopyridinium precursors substantiate the signal assignment in the bispyridiniu