A comparison of safety and efficacy of sublingual captopril with sublingual nifedipine in hypertensive crisis
✍ Scribed by Kani Gemici; Yüksel Karakoç; Alpaslan Ersoy; Ibrahim Baran; Sümeyye Güllülü; Jale Cordan
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 376 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1061-1711
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📜 SIMILAR VOLUMES
A rabbit model for investigating sublingual drug absorption was established yielding results consistent with clinical data reported in the literature. Using propranolol as a model compound the effect of formulation and dosing variables was explored as a means to characterize the limiting parameters
Objective: The pharmacokinetics and pharmacodynamics of buffered sublingual captopril were assessed in patients with congestive heart failure (CHF). Methods: The study was carried out in a randomised single-blind cross-over fashion (n = 6, 4 males and 2 females) and involved two study days, at least