A comparison of ornithine decarboxylase and S-adenosylmethione decarboxylase activity in human large bowel mucosa, polyps, and colorectal adenocarcinoma
โ Scribed by Lemuel Herrera-Ornelas; Carl Porter; Paula Pera; William Greco; Nicholas J. Petrelli; Arnold Mittelman
- Book ID
- 116010129
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 455 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0022-4804
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Ornithine decarboxylase (ODC) activity and differential polyamine composition have been studied in macroscopically normal mucosa, adjacent mucosa, and neoplastic tissue of 95 patients with adenocarcinomas of stomach and large intestine. In tumors, we found increased ODC activity and polyamine conten
## Abstract Ornithine decarboxylase may be a useful biomarker for risk of neoplasia in colorectal tissues. Investigators have reported enzyme activities varying by as much as 10โ to 20โfold using variations of the usual ^14^CO~2~ release assay. We have examined the effect of different methodologic