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Ornithine decarboxylase activity and polyamine content in adenocarcinomas of human stomach and large intestine

โœ Scribed by N. K. Berdinskikh; N. A. Ignatenko; S. P. Zaletok; K. P. Ganina; V. A. Chorniy

Publisher
John Wiley and Sons
Year
1991
Tongue
French
Weight
365 KB
Volume
47
Category
Article
ISSN
0020-7136

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โœฆ Synopsis

Ornithine decarboxylase (ODC) activity and differential polyamine composition have been studied in macroscopically normal mucosa, adjacent mucosa, and neoplastic tissue of 95 patients with adenocarcinomas of stomach and large intestine. In tumors, we found increased ODC activity and polyamine content as compared with surrounding mucosa. ODC activity in macroscopically normal tissue of patients with tumors of stomach and large intestine increased as the disease progressed. An inverse relationship was observed between ODC activity in adenocarcinomas and differentiation.

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