A Comparison of Oral and Rectal Absorption of L-Dopa Esters in Rats and Mice
โ Scribed by Joseph A. Fix; Jose Alexander; Margot Cortese; Karen Engle; Paula Leppert; A. J. Repta
- Book ID
- 110341494
- Publisher
- Springer US
- Year
- 1990
- Tongue
- English
- Weight
- 710 KB
- Volume
- 07
- Category
- Article
- ISSN
- 0724-8741
No coin nor oath required. For personal study only.
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In Experiment 1, rats of 5, 10, 15, and 20 days of age were injected with L-DOPA to elicit stepping and videotaped while suspended in air and in warm water. Inter- and intralimb coordination were similar for L-DOPA-induced air-stepping and swimming at all ages. Other parameters of locomotion, such a
The absorption kinetics of different pharmaceutical formulations of orally and rectally administered flecainide have been assessed in a cross-over study in 7 healthy volunteers. The subjects received single doses of flecainide after a washout period of at least one week. A tablet, an oral solution,