We evaluated laser scanning cytometry (LSC) by comparing nuclear DNA ploidy determined by LSC and by flow cytometry (FCM) i n 77 samples of human colorectal cancer from 48 patients. Both methods revealed an aneuploid peak in 30 (62.5%) of the cases, although two samples that were aneuploid by LSC we
A comparison of flow cytometry and immunohistochemistry in human colorectal cancers
β Scribed by AXEL COSMUS PYNDT DIEDERICHSEN; TINE PLATO HANSEN; OLE NIELSEN; CLAUS FENGER; JENS CHRISTIAN JENSENIUS; PER BORUP CHRISTENSEN; TOM KRISTENSEN; JESPER ZEUTHEN
- Book ID
- 111277841
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 944 KB
- Volume
- 106
- Category
- Article
- ISSN
- 0365-5555
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## Abstract We wished to better understand the role of aneuploidy during the progression of human colorectal cancer. Fresh or frozen multiple samples from 221 human colorectal adenomas, 93 carcinomas, and corresponding control mucosa were investigated using highβresolution DNA flow cytometry. A tot
The DNA content in 37 tumors from 34 women with gynecological cancer was measured by flow cytometry (FCM) and interactive image cytometry (ICM). Agreement was obtained in 81% of cases as regards ploidy levels, but seven tumors (19%) showed different ploidies. Of these, five were classified as diploi