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A Comparative Study on the Effect of Hydrophobicity and Net Positive Charge on the Antibacterial and Anti- Endotoxin Activities of Antimicrobial Peptides

✍ Scribed by Rosenfeld, Yosef; Lev, Naama; Shai, Yechiel

Book ID
119206625
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
36 KB
Volume
98
Category
Article
ISSN
0006-3495

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## Abstract In our previous study, we utilized a 26‐residue amphipathic α‐helical antimicrobial peptide L‐V13K (Chen et al., Antimicrob Agents Chemother 2007, 51, 1398–1406) as the framework to study the effects of peptide hydrophobicity on the mechanism of its antimicrobial action. In this study,