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A comparative study of drug metabolism in the isolated perfused liver and in vivo in rats

✍ Scribed by C. Von Bahr; B. Alexanderson; D.L. Azarnoff; F. Sjöqvist; S. Orrenius

Book ID
118320624
Publisher
Elsevier Science
Year
1970
Tongue
English
Weight
426 KB
Volume
9
Category
Article
ISSN
0014-2999

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Metabolic effects of acetaminophen. Stud
Metabolic effects of acetaminophen. Studies in the isolated perfused rat liver
✍ Ana Maria Itinose; Marlene Leiko Doi Sakuno; Adelar Bracht 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 989 KB

The effects of acetaminophen on the metabolism of the isolated perfused rat liver were investigated. The following results were obtained: (1) Acetaminophen increased glucose release and glycolysis from endogenous glycogen (glycogenolysis). (2) Oxygen uptake, gluconeogenesis from either pyruvate or