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A comparative analysis of family-based and population-based association tests using whole genome sequence data

✍ Scribed by Jin J Zhou,Wai-Ki Yip,Michael H Cho,Dandi Qiao,Merry-Lynn N McDonald…

Book ID
126380040
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
580 KB
Volume
8
Category
Article
ISSN
1753-6561

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## Abstract Based on the symmetry of transmitted/nontransmitted alleles from heterozygous parents under the null hypothesis of no association, the work proposed here establishes a general statistical framework for constructing association tests with data from nuclear families with multiple affected