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A Common Variant in the PNPLA3 Gene is a Risk Factor for Non-Alcoholic Fatty Liver Disease in Obese Taiwanese Children

✍ Scribed by Yu-Cheng Lin; Pi-Feng Chang; Fu-Chang Hu; Wei-Shiung Yang; Mei-Hwei Chang; Yen-Hsuan Ni


Book ID
113746396
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
164 KB
Volume
158
Category
Article
ISSN
1097-6833

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The genetic factors associated with susceptibility to nonalcoholic fatty liver disease (NAFLD) in pediatric obesity remain largely unknown. Recently, a nonsynonymous single-nucleotide polymorphism (rs738409), in the patatin-like phospholipase 3 gene (PNPLA3) has been associated with hepatic steatosi