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A common intermediate in the biosynthesis of the O8 and O9 antigens of Escherichia coli

โœ Scribed by Gerd Goldemann; Shiro Kanegasaki; Klaus Jann

Book ID
109310309
Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
191 KB
Volume
5
Category
Article
ISSN
0378-1097

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Structural determination of the capsular
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The primary structure of the acidic capsular antigen of Escherichia coli 08:K25:H9 was shown by monosaccharide analysis, methyl&on analysis, and by 1D and 2D 'H and 13C NMR spectroscopy to be composed of linear tetrasaccharide repeating units having the structure: + 2) -fi-D-GkpA-( 1 --, 3) -cY-D-Ga

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The structure of the capsular polysaccharide from Escherichia coli 08:KS:H4 has been elucidated, using mainly methylation analysis, Smith degradation, and lD-and 2D-n.m.r. spectroscopy. The polysaccharide, after removal of bound lipid, was found to be composed of repeating units of the linear tetras