A common gain of function of p53 cancer mutants in inducing genetic instability
✍ Scribed by Liu, D P; Song, H; Xu, Y
- Book ID
- 109971160
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 672 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0950-9232
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## Abstract In human breast cancer, mutations in the __p53__ gene are associated with poor prognosis. However, analysis of patient data so far did not clarify, whether missense point mutations in the __p53__ gene, in addition to causing loss of wild‐type p53 function, also confer a gain of function