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A common core for binding single-stranded DNA: structural comparison of the single-stranded DNA-binding proteins (SSB) from E. coli and human mitochondria

โœ Scribed by Gordon Webster; Jochen Genschel; Ute Curth; Claus Urbanke; ChulHee Kang; Rolf Hilgenfeld


Book ID
117107855
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
669 KB
Volume
411
Category
Article
ISSN
0014-5793

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Interaction of E. coli Single-Stranded D
โœ Genschel, Jochen; Curth, Ute; Urbanke, Claus ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Walter de Gruyter GmbH & Co. KG ๐ŸŒ English โš– 232 KB

The 3-5 single-stranded DNA (ssDNA) degrading exonuclease I of E. coli directly interacts with the E. coli ssDNA binding protein (EcoSSB). Analytical ultracentrifugation shows that all 4 carboxy-termini of an EcoSSB tetramer bind exonuclease I. Binding is weakened by increasing salt concentrations,