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A cohort study of the nature of paroxysmal nocturnal hemoglobinuria clones and PIG-A mutations in patients with aplastic anemia

โœ Scribed by Wanchai Wanachiwanawin; Uamporn Siripanyaphinyo; Nattawan Piyawattanasakul; Taroh Kinoshita


Book ID
114676139
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
208 KB
Volume
76
Category
Article
ISSN
0902-4441

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The relationships between paroxysmal nocturnal hemogloblnuria (PNH), aplastlc anemia (AA), and myelodysplastlc syndrome (MDS) are not clear. Here we describe a patient, J20, who developed a reciprocal translocation of chromosome 12 and PNH during follow-up of AA. All metaphases In CD59-deflcient bon