A Clinically Orientated Approach for Combining Discordant and Concordant Sib Pairs
✍ Scribed by Andreas Ziegler; Johannes Hebebrand; Helmut Schäfer
- Book ID
- 102761378
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 570 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0323-3847
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📜 SIMILAR VOLUMES
The degree of anemia in p'-thalassemia/hemoglobin E disease is highly variable. As part of an attempt to identify determinants of this variability of severity we studied concordance and discordance of hemoglobin levels among sib pairs. The distribution of differences of hemoglobin levels in 216 sib
For the analysis of quantitative traits in nuclear families, extreme discordant sib pairs proved to be more powerful than unselected sib pairs. Here, we present a test that makes use of selected pairs and, in addition, restricts the parameters of the identical-by-descent distribution analogously to