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A clinical trial of hyperalimentation in children with metastatic malignancies

โœ Scribed by Van Eys, J. ;Copeland, E. M. ;Cangir, A. ;Taylor, G. ;Teitell-Cohen, B. ;Carter, P. ;Ortiz, C.


Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
777 KB
Volume
8
Category
Article
ISSN
0098-1532

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โœฆ Synopsis


Abstract

In a controlled, randomized prospective clinical trial the utility of intravenous hyperalimentation (IVH) in the administration of and tolerance to chemotherapy was tested. The conclusions reached were 1) IVH is safe with a tolerable infection rate; 2) infectious complications correlate significantly with the nutritional status of the patient, with the presence of IVH being only a secondary factor; 3) IVH may be used to rehabilitate patients nutritionally, even those on intensive chemoterhapy; 4) the ability to deliver chemotherapy to patients seems to be improved by IVH, especially in malnourished patients in a late stage of disease.


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## Abstract A prospective randomized clinical trial was undertaken to test the efficacy of total parenteral nutrition (TPN) among previously untreated children receiving abdominal/pelvic irradiation with or without adjuvant chemotherapy who were at risk for weight loss, malnutrition, and complicati