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A class of 2D graphical representations of RNA secondary structures and the analysis of similarity based on them

✍ Scribed by Yu-Hua Yao; Xu-Ying Nan; Tian-Ming Wang

Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 230 KB
Volume: 26
Category: Article
ISSN: 0192-8651
DOI: 10.1002/jcc.20271

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✦ Synopsis

Abstract

Based on the concepts of cell and system of graphical representation, a class of 2D graphical representations of RNA secondary structures are given in terms of classifications of bases of nucleic acids. The representations can completely avoid loss of information associated with crossing and overlapping of the corresponding curve. As an application, we make quantitative comparisons for a set of RNA secondary structures at the 3′‐terminus of different viruses based on the graphical representations. The examination of similarities/dissimilarities illustrates the utility of the approach. © 2005 Wiley Periodicals, Inc. J Comput Chem 26: 1339–1346, 2005

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