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A chronic myelocytic leukemia case bearing deletions on the three chromosomes involved in a variant t(9;22;11)

โœ Scribed by Luisa Anelli; Francesco Albano; Antonella Zagaria; Arcangelo Liso; Maria Grazia Roberti; Mariano Rocchi; Giorgina Specchia


Book ID
114135705
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
178 KB
Volume
148
Category
Article
ISSN
0165-4608

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Genomic deletions on other chromosomes i
โœ Francesco Albano; Giorgina Specchia; Luisa Anelli; Antonella Zagaria; Clelia Tiz ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 564 KB

## Abstract The Philadelphia (Ph) chromosome is the cytogenetic hallmark of chronic myeloid leukemia (CML) and is observed in more than 90% of CML cases. At diagnosis, in 5โ€“10% of CML patients the Ph chromosome is derived from variant translocations other than the standard t(9;22). Deletions adjace