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A Chiron Approach to the Total Synthesis of (+)-Aculeatin D

โœ Scribed by Zhen, Zhi-Bin; Gao, Jian; Wu, Yikang


Book ID
111654007
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
277 KB
Volume
73
Category
Article
ISSN
0022-3263

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## Abstract The stereocontrolled synthesis of goniothalesdiol A, a dihydroxylated tetrahydropyran compound, has been accomplished using Dโ€ribose as chiral precursor. The key steps involved are aryl __Grignard__ reaction, stereoselective alkoxyโ€directed keto reduction, and intramolecular oxyโ€__Micha