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A chiral samarium-based catalyst for the asymmetric Meerwein-Ponndorf-Verley reduction

✍ Scribed by Evans, David A.; Nelson, Scott G.; Gagne, Michel R.; Muci, Alexander R.


Book ID
115469858
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
270 KB
Volume
115
Category
Article
ISSN
0002-7863

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Asymmetric Meerwein-Ponndorf-Verley redu
✍ Ding Zong-Biao; Cheng Ke-Jun; Wu Shi-Hui 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 372 KB

## Abstract A new type of chiral 1,1′‐binaphthol(BINOL) derived samarium complex, prepared from (__R__)‐or (__S__)‐BINOL and SmCl~3~, serves as an enantioselective catalyst for the Meerwein‐Ponndorf‐Verley (MPV) reduction in the presence of Molecular Sieves 4Å(MS 4Å). Moderate enantioselectivity wa