Structured models of antibiotic fermentation that quantify maturation and aging of product forming biomass are fitted to experimental data. Conditions of superiority of repeated fed batch cultivation are characterized on the basis of a performance criterion that includes penicillin productivity and
A cellular automata model for simulating fed-batch penicillin fermentation process
β Scribed by Yu, Naigong ;Ruan, Xiaogang
- Book ID
- 107382520
- Publisher
- Higher Education Press and Springer
- Year
- 2006
- Tongue
- English
- Weight
- 608 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1673-3509
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## Abstract Two kinds of mathematical models have been developed for batch penicillin fermentations: (1) general models, based on averaged, nondimensionalized cell and penicillin synthesis curves from plant, scale fermentors and (2) particular models developed from specific sets of experimental dat
A mathematical model is formulated to describe trends in biomass and penicillin formation as well as substrate consumption for fed-batch cultivations. The biomass is structured into three morphological compartments, and glucose and corn steep liquor are considered as substrates for growth. Penicilli