## Abstract Cell lines have been established from placentas of various strains of mice by __in vitro__ cultivation. The established lines appear to be trophoblast cells as judged from their production of gonadotropinβlike substance and steroid hormones. The cell lines lack detectable Hβ2 antigen, F
A cell line from an induced carcinoma of mouse rectum
β Scribed by L. M. Franks; Valerie J. Hemmings
- Book ID
- 104505018
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 617 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0022-3417
No coin nor oath required. For personal study only.
β¦ Synopsis
A tissue culture cell line has been established from one out of seven induced carcinomas of mouse large intestine. The cells have an epithelial morphology and form tumour acini in vitro. Electron microscopy shows that the cells have retained some differentiated characters, including junctional complexes and microvilli with attached glycoprotein strands both in the acini and at the free margins of the cell sheets.
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A new cell line derived from a woodchuck hepatocellular carcinoma serially transplanted in athymic nude mice has been established and named WH257GE10. The original tumor in the nude mouse system produces woodchuck hepatitis surface antigen and albumin. In addition, woodchuck hepatitis virus DNA is i