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A cell-based immunocytochemical assay for monitoring kinase signaling pathways and drug efficacy

✍ Scribed by Huaxian Chen; Joy Kovar; Sean Sissons; Karen Cox; William Matter; Fred Chadwell; Peng Luan; Chris J. Vlahos; Amy Schutz-Geschwender; D. Michael Olive

Book ID
108047797
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
985 KB
Volume
338
Category
Article
ISSN
0003-2697

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## Abstract In this age of targeted therapy, the failure of most current drug‐discovery efforts to yield safe, effective, and inexpensive drugs has generated widespread concern. Successful drug development has been stymied by a general focus on target selection rather than clinical safety and effic