A Catalytic Enantioselective Imino-Reformatsky Reaction
β Scribed by Pier Giorgio Cozzi
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 88 KB
- Volume
- 348
- Category
- Article
- ISSN
- 1615-4150
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## on the occasion of his 70th birthday The Reformatsky reaction, [1] one of the classic "named" reactions, was discovered almost 120 years ago and is still widely used in synthesis. [2] It consists of the zinc-induced formation of b-hydroxyalkanoates from a-halocarbonyl compounds and aldehydes or
1 mol% of catalyst is sufficient: The hetero Diels-Alder reaction of Ξ±-imino esters 1 with activated conjugated dienes 2 (R=H, Me) needs only 1 mol% of a 2,2'-bis(diarylphosphanyl)-1,1'-binaphthyl (BINAP) copper(I) complex as the catalyst to generate the adducts 3 in good yields and with enantiosele