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A Catalyst for the selective dehydrogenation of 4,5,6,7-tetrahydroindole into indole

โœ Scribed by Trofimov, B. A.; Mikhaleva, A. I.; Schmidt, E. Yu.; Protsuk, N. I.; Ivanov, A. V.; Ryapolov, O. A.

Book ID
110160314
Publisher
Springer
Year
2011
Tongue
English
Weight
123 KB
Volume
437
Category
Article
ISSN
0012-5008

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Reduction of the indole ring system: syn
Reduction of the indole ring system: synthesis of 4,5,6,7-tetrahydroindoles
โœ Casey C. McComas; David L. Van Vranken ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 250 KB

A general two-step procedure for the reduction of indoles to the corresponding 4,5,6,7-tetrahydroindoles has been developed. A regioselective Birch reduction followed by catalytic hydrogenation is employed to accomplish this transformation. Yields for the sensitive pyrrole products are typically bet