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A Case of Competitive Demethylation by Boron Tribromide-methyl Sulfide Complex. A New Route to Oxazoloquinolines

✍ Scribed by Bévière, Corinne; Rocher, Richard; Chenault, Jacques


Book ID
120974784
Publisher
Taylor and Francis Group
Year
1998
Tongue
English
Weight
129 KB
Volume
28
Category
Article
ISSN
0039-7911

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Selective O-demethylation of the ortho methyl catecholate of N,N',N"-tris-(2,3dimethoxybenzeyl)-l,l,l-tris-(L-methioninemehyl)-ethane (2) has been accomplished by boron tribromide. The intramolecular nucleophilic attack of divalent sulphur on methyl enhance this cleavage, favours this selctivity and