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A case of brain-biopsy proven progressive multifocal leukoencephalopathy: Pathological findings and analysis of JC virus regulatory region

โœ Scribed by Yosuke Wakutani; Yasutaka Shimizu; Hiroshi Miura; Kenji Nakashima; Toshiya Nakano; Eisaku Ohama; Chie Sugimoto; Yoshiaki Yogo; Yoshiyasu Kobayashi; Kazuo Nagashima


Book ID
108957651
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
894 KB
Volume
18
Category
Article
ISSN
0919-6544

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Genetic analysis of JC virus and BK viru
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A case of acute progressive multifocal leukoencephalopathy (PML) with hyper IgM syndrome 1 is reported. Viral DNA and VP1 protein of JC virus (JCV) and BK virus (BKV) were detected by immunohistochemistry, in situ hybridization, seminested polymerase chain (PCR) and PCR-restriction enzyme analysis.