A case of acute promyelocytic leukemia presenting with a nonleukemic granulocytic sarcoma of the ovary, with subsequent development of acute myeloid leukemia associated with t(8;21)
β Scribed by Xingbing Wang; Huilan Liu; Zhiwei Wu; Xiucai Xu; Xin Chen; Zhimin Zhai; Zimin Sun
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 140 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0145-2126
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π SIMILAR VOLUMES
An 8 2 I translocation is a common chromosome abnormality associated with acute myeloblastic leukemia with maturation (M2 of French-American-British (FAB) classification). W e have isolated chromosome 2 I Nod linking clones; pulsed field gel electrophoresis analysis with one clone (LL263) detected a
## BACKGROUND. The association between t(8;21) and granulocytic sarcoma (GS) is well known, but to the authors' knowledge the prognostic significance of GS in these patients has not been defined clearly. ## METHODS. Between January 1990 and July 1999 174 children with acute myeloid leukemia were