A case of acute lymphoblastic leukemia with t(10;19)(q26;q13)
β Scribed by M. De Braekeleer; M.C. Poon; J. Russell; C.C. Lin
- Book ID
- 119103137
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 214 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0165-4608
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The recurrent t(14;19)(q32;q13) translocation associated with chronic B-cell lymphoproliferative disorders, such as atypical chronic lymphocytic leukemia, results in the juxtaposition of the IGH@ and BCL3 genes and subsequent overexpression of BCL3. We report six patients with B-cell precursor acute
## Abstract The t(1;19)(q23;p13), which results in a fusion of __TCF3__ (previously __E2A__) at 19p13 with __PBX1__ at 1q23, is one of the most common translocations in acute lymphoblastic leukemia (ALL). It is seen either as a balanced t(1;19) or as an unbalanced der(19)t(1;19); occasional cases w