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A case of acute encephalopathy with hemophagocytic lymphohistiocytosis and clonal T-cell expansion

✍ Scribed by Taizo Wada; Kashiku Nishiura; Mondo Kuroda; Erika Asai; Quang Van Vu; Tomoko Toma; Yo Niida; Akihiro Yachie


Book ID
113499076
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
282 KB
Volume
34
Category
Article
ISSN
0387-7604

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## BACKGROUND. Although familial hemophagocytic lymphohistiocytosis (FHL) has been considered a T-cell disorder, to the authors' knowledge there are no previous reports on the clonal basis of FHL. In the current study the authors analyzed the clonality of T-cells in two FHL patients at the time of