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A C 2 -Symmetric Chiral Pool-Based Flexible Strategy: Synthesis of (+)- and (−)-Shikimic Acids, (+)- and (−)-4- epi -Shikimic Acids, and (+)- and (−)-Pinitol

✍ Scribed by Ananthan, Bakthavachalam; Chang, Wan-Chun; Lin, Jhe-Sain; Li, Pin-Hui; Yan, Tu-Hsin


Book ID
124062358
Publisher
American Chemical Society
Year
2014
Tongue
English
Weight
457 KB
Volume
79
Category
Article
ISSN
0022-3263

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A novel strategy for the enantioselective synthesis of several a-hydroxy carboxylic acids by the nucleophilic alkylation of chiral 3-hydroxy-(YS, 8aS)-perhydropyrrolo [2,1-C] [1,4] oxazin -4 one is reported.