## Abstract It has been recently established that Gβproteinβcoupled receptors (GPCRs) can be constitutively active, i.e., they can be active in the absence of an agonist. This activity can be inhibited by soβcalled inverse agonists. For a number of GPCRs, such inverse agonists have been developed a
A Bioluminescent Assay for Agonist Activity at Potentially Any G-Protein-Coupled Receptor
β Scribed by Jenny Stables; Andrew Green; Fiona Marshall; Neil Fraser; Emma Knight; Martine Sautel; Graeme Milligan; Melanie Lee; Stephen Rees
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 288 KB
- Volume
- 252
- Category
- Article
- ISSN
- 0003-2697
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