✦ LIBER ✦

Evidence for the Existence of a Specific G Protein-Coupled Receptor Activated by Guanosine

✍ Scribed by Prof. Rosaria Volpini; Prof. Gabriella Marucci; Dr. Michela Buccioni; Dr. Diego Dal Ben; Dr. Catia Lambertucci; Dr. Carmen Lammi; Dr. Ram C. Mishra; Ajiroghene Thomas; Prof. Gloria Cristalli

Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 264 KB
Volume: 6
Category: Article
ISSN: 1860-7179
DOI: 10.1002/cmdc.201100100

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: The G Protein-Coupl

ChemInform Abstract: The G Protein-Coupled Protease Receptor PAR (Protease-Activated Receptor) as a Novel Target for Drug Development

✍ Atsufumi Kawabata 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 25 KB 👁 2 views

Evidence for positive selection in the e

Evidence for positive selection in the extracellular domain of human cytomegalovirus encoded G protein-coupled receptor US28

✍ Xiaoyan Gong; Abinash Padhi 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 273 KB

## Abstract The human cytomegalovirus (HCMV)‐encoded chemokine receptor US28 is also a seven‐transmembrane G‐protein coupled receptor, whose signaling pathway is known for its involvement in host immune system evasion. HCMV infection can result in serious disease in immunocompromised individuals an

Functional Selectivity of G Protein-Coup

Functional Selectivity of G Protein-Coupled Receptor Ligands: New Opportunities for Drug Discovery. Edited by Kim A. Neve.

✍ Christoph Boss 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 119 KB 👁 1 views

Generation of RNA Aptamers to the G-Prot

Generation of RNA Aptamers to the G-Protein-Coupled Receptor for Neurotensin, NTS-1

✍ Dion A. Daniels; Awinder K. Sohal; Stephen Rees; Reinhard Grisshammer 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 230 KB

G-protein-coupled receptors (GPCRs) are integral membrane proteins involved in signal transduction and constitute major drug targets for disease therapy. Aptamers, which are globular RNA or DNA molecules evolved to specifically bind a target, could represent a valuable tool with which to probe the r

The N-terminal domain of GPR61, an orpha

The N-terminal domain of GPR61, an orphan G-protein-coupled receptor, is essential for its constitutive activity

✍ Masaru Toyooka; Takashi Tujii; Shigeki Takeda 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 191 KB

## Abstract G‐protein‐coupled receptor 61 (GPR61) is an orphan receptor that is abundantly expressed in the brain, which suggests its involvement in various physiological functions in the central nervous system. It couples with Gs and shows constitutive activity. To investigate the role of the N‐te

A serotonin receptor antagonist induces

A serotonin receptor antagonist induces oocyte maturation in both frogs and mice: Evidence that the same G protein-coupled receptor is responsible for maintaining meiosis arrest in both species

✍ Yinglun Sheng; Ling Wang; X. Shawn Liu; Véronique Montplaisir; Mario Tiberi; Jay 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 407 KB

## Abstract Accumulating evidence has indicated that vertebrate oocytes are arrested at late prophase (G2 arrest) by a G protein coupled receptor (GpCR) that activates adenylyl cyclases. However, the identity of this GpCR or its regulation in G2 oocytes is unknown. We demonstrated that ritanserin (