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A bicyclic and hsst2 selective somatostatin analogue: design, synthesis, conformational analysis and binding

✍ Scribed by Eliezer Falb; Yoseph Salitra; Tamar Yechezkel; Moshe Bracha; Pninit Litman; Roberto Olender; Rakefet Rosenfeld; Hanoch Senderowitz; Shaokai Jiang; Murray Goodman

Book ID
108479113
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
396 KB
Volume
9
Category
Article
ISSN
0968-0896

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Conformational analysis of a potent SSTR
Conformational analysis of a potent SSTR3-selective somatostatin analogue by NMR in water solution
✍ Margarida Gairí; Pilar Saiz; Sergio Madurga; Xavier Roig; Judit Erchegyi; Steven 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 286 KB

## Abstract The three‐dimensional structure of a potent SSTR3‐selective analogue of somatostatin, cyclo(3–14)H‐Cys^3^‐Phe^6^‐Tyr^7^‐D‐Agl^8^(N^β^ Me, 2‐naphthoyl)‐Lys^9^‐Thr^10^‐Phe^11^‐Cys^14^‐OH (des‐AA^1, 2, 4, 5, 12, 13^[Tyr^7^, D‐Agl^8^(N^β^ Me, 2‐naphthoyl)]‐SRIF) (peptide **1**) has been det