## Abstract Heteroconjugate (HC) antibody has a potential use in cancer biotherapy because of its ability to mimic antigenic specificity and induce cytotoxicity in the activated lymphocytes against various tumor cells. This study investigated the effects of HC antibody (anti‐CD3 MAb x anti‐p97 mela
✦ LIBER ✦
A B7-1-transfected human melanoma line stimulates proliferation and cytotoxicity of autologous and allogeneic lymphocytes
✍ Scribed by Josep Sulé-Suso; Flavio Arienti; Cecilia Melani; Mario Paolo Colombo; Giorgio Parmiani
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Volume
- 25
- Category
- Article
- ISSN
- 0014-2980
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## Abstract The influence of interleukin 2 (IL2) on the cytotoxic activity of lymphocytes from patients with melanoma against autologous and a variety of allogeneic melanoma cells was studied. IL2 was produced from blood lymphocytes cultured for 24 h with phytohaemagglutinin (PHA) and purified by m