## Potentiation of immunogenicity of malignant cells by gene transduction provides a unique opportunity for immune targeting of human cancers in vivo. This approach is undoubtedly influenced by the ability of the malignant cells to process and present endogenously target epitopes on their cell surf
โฆ LIBER โฆ
B7.1 gene transduction of human renal-cell-carcinoma cell lines restores the proliferative response and cytotoxic function of allogeneic T cells
โ Scribed by Christine Bain; Y. Merrouche; Isabelle Puisieux; Adeline Duc; Mario Paolo Colombo; Marie Favrot
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- French
- Weight
- 795 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0020-7136
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Human renal cell carcinoma (RCC) is a common malignant disease of the kidney characterized by dedifferentiation of renal epithelial cells. Our previous experiments showed that most RCCs have a loss of function of the tissue-specific transcription factor hepatocyte nuclear factor (HNF) 1ฮฑ. Detailed a