High throughput synthesis of 2,3,6-trisu
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Yangmei Li; Marc Giulianotti; Richard A. Houghten
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Article
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2011
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Elsevier Science
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French
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A facile approach to the synthesis of 2,3,6-trisubstituted-5,6-dihydroimidazo[2,1-b]thiazole was reported. A resin bound cyclic thiourea was formed by the treatment of a resin bound diamine with 1,1'-thiocarbonyldiimidazole, and then reacted with a ฮฑ-haloketone to generate a resin bound isothiourea.