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A 5′ Splice Site Enhances the Recruitment of Basal Transcription Initiation Factors In Vivo

✍ Scribed by Christian Kroun Damgaard; Søren Kahns; Søren Lykke-Andersen; Anders Lade Nielsen; Torben Heick Jensen; Jørgen Kjems

Book ID
116754503
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
986 KB
Volume
29
Category
Article
ISSN
1097-2765

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✍ Rhett P. Ketterling; Joni B. Drost; William A. Scaringe; Dong-zhou Liao; Jing-zh 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 497 KB 👁 2 views

Small consensus sequences have been defined for RNA splicing, but questions about splicing in humans remain unanswered. Analysis of germline mutations in the factor IX gene offers a highly advantageous system for studying the mutational process in humans. In a sample of 860 families with hemophilia