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Cell-Type-Restricted Binding of the Transcription Factor NFAT to a Distal IL-4 Enhancer In Vivo

✍ Scribed by Suneet Agarwal; Orly Avni; Anjana Rao


Book ID
117722643
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
385 KB
Volume
12
Category
Article
ISSN
1074-7613

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## Abstract The basis of the adjuvant effect of IL‐1 on the clonal expansion of Ag‐specific CD4 T cells was measured __in vivo__ using the TCR transgenic T cell adoptive transfer method. Injection ofAg plus IL‐1 caused naive CD4 T cells to proliferate to a greater extent than did injection of Ag al