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A 19 F NMR Label to Substitute Polar Amino Acids in Peptides: A CF 3 -Substituted Analogue of Serine and Threonine

โœ Scribed by Tkachenko, Anton N.; Mykhailiuk, Pavel K.; Afonin, Sergii; Radchenko, Dmytro S.; Kubyshkin, Vladimir S.; Ulrich, Anne S.; Komarov, Igor V.

Book ID
118751917
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
480 KB
Volume
125
Category
Article
ISSN
0044-8249

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## Abstract The conformation, alignment and dynamic behavior of membraneโ€bound peptides is readily accessible by solidโ€state ^19^Fโ€NMR spectroscopy, but it has been difficult to incorporate suitable ^19^Fโ€labelled amino acids into synthetic peptides. To avoid the drawbacks of previously used labels