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A 13-year longitudinal study of the impact of double mutations in the core promoter region of hepatitis B virus on HBeAg seroconversion and disease progression in patients with genotype C chronic active hepatitis

โœ Scribed by J. W. Jang; Y. C. Lee; M. S. Kim; S. Y. Lee; S. H. Bae; J. Y. Choi; S. K. Yoon


Book ID
108885944
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
495 KB
Volume
14
Category
Article
ISSN
1352-0504

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## Abstract It has been reported that genetic polymorphisms near the __IL28B__ gene or amino acid substitutions in hepatitis C virus (HCV) core protein are associated with the clinical outcome of peginterferon (PEGโ€IFN) and ribavirin combination therapy. The impact of these factors on the pure sens