9p21 deletion in the diagnosis of malignant mesothelioma, using fluorescence in situ hybridization analysis
โ Scribed by Maiko Takeda; Takahiko Kasai; Yasunori Enomoto; Masato Takano; Kouhei Morita; Eiji Kadota; Akitaka Nonomura
- Book ID
- 115176214
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 363 KB
- Volume
- 60
- Category
- Article
- ISSN
- 1320-5463
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We examined 82 cases of primary non-small cell lung cancer (NSCLC) for loss of heterozygosity (LOH) at the chromosome 9p21-24 region using 16 microsatellite markers. A total of 52 tumors (63%) displayed LOH, and 25 of these cases displayed LOH for all markers. Two cases had small hemizygous losses c