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99mTc-labeled benzothiazole and stilbene derivatives as imaging agents for Aβ plaques in cerebral amyloid angiopathy

✍ Scribed by Jia, Jianhua ;Cui, Mengchao ;Dai, Jiapei ;Wang, Xuedan ;Ding, Yu-Shin ;Jia, Hongmei ;Liu, Boli


Book ID
126035734
Publisher
The Royal Society of Chemistry
Year
2014
Tongue
English
Weight
534 KB
Volume
5
Category
Article
ISSN
2040-2503

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Based on the conjugate strategy, two neutral (99m)Tc labeled 2-(1-(6-(dialkylamino)naphthalen-2-yl)ethylidene)malononitrile (DDNP) and 1-(6-(dialkylamino)naphthalen-2-yl)ethanone (ENE) derivatives, and their corresponding rhenium complexes were synthesized. In vitro fluorescent staining indicated th