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99mTc/Re complexes based on flavone and aurone as SPECT probes for imaging cerebral β-amyloid plaques

✍ Scribed by Masahiro Ono; Ryoichi Ikeoka; Hiroyuki Watanabe; Hiroyuki Kimura; Takeshi Fuchigami; Mamoru Haratake; Hideo Saji; Morio Nakayama


Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
623 KB
Volume
20
Category
Article
ISSN
0960-894X

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✍ Mengchao Cui; Ruikun Tang; Zijing Li; Huiying Ren; Boli Liu 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 574 KB

Based on the conjugate strategy, two neutral (99m)Tc labeled 2-(1-(6-(dialkylamino)naphthalen-2-yl)ethylidene)malononitrile (DDNP) and 1-(6-(dialkylamino)naphthalen-2-yl)ethanone (ENE) derivatives, and their corresponding rhenium complexes were synthesized. In vitro fluorescent staining indicated th