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964 EXPRESSION PROFILE OF WNT PATHWAY MEMBERS IN PROSTATE CANCER AND THEIR REGULATION BY ZOLEDRONIC ACID

✍ Scribed by Thiele, Silvia; Rauner, Martina; Goettsch, Claudia; Rachner, Tilman; Benad, Peggy; Fuessel, Susanne; Erdmann, Kati; Hamann, Christine; Baretton, Gustavo; Wirth, Manfred P.; Jakob, Franz Jakob; Hofbauer, Lorenz


Book ID
118484714
Publisher
Lippincott Williams and Wilkins
Year
2012
Tongue
English
Weight
47 KB
Volume
187
Category
Article
ISSN
0022-5347

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Expression profile of WNT molecules in p
✍ Sylvia Thiele; Martina Rauner; Claudia Goettsch; Tilman D. Rachner; Peggy Benad; πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 537 KB

Skeletal metastases represent a frequent complication in patients with advanced prostate cancer (PCa) and often require bisphosphonate treatment to limit skeletal-related events. Metastasized PCa cells disturb bone remodeling. Since the WNT signaling pathway regulates bone remodeling and has been im