956 NFAT5 Regulates Intestinal Cell Differentiation by Negatively Regulating AKT
โ Scribed by Qingding Wang; Zheng Guo; Yuning Zhou; Xin Li; Tianyan Gao; Mark Evers
- Book ID
- 119431490
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 65 KB
- Volume
- 138
- Category
- Article
- ISSN
- 0016-5085
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
PTEN is a tumor suppressor with sequence homology to protein tyrosine phosphatases and the cytoskeletal protein tensin. mPTEN-mutant mouse embryos display regions of increased proliferation. In contrast, mPTEN-deficient immortalized mouse embryonic fibroblasts exhibit decreased sensitivity to cell d
In vitro experiments have shown that the establishment of cell-cell contacts in intestinal epithelial cell cultures is a critical step in initiating ERK inhibition, cell cycle arrest, and induction of the differentiation process. Herein, we determined the mechanisms through which E-cadherin-mediated