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955 Associations Between Genetic Variants in the Glucocorticoid Receptor (GR) Gene and Corticosteroid Dependency in Paediatric-Onset Crohn's Disease

โœ Scribed by Alfreda Krupoves; David R. Mack; Emile Levy; Colette Deslandres; Philippe Lambrette; Houda H. Feguery; Jinsong Dong; Vytautas Bucionis; Ernest G. Seidman; Devendra K. Amre


Book ID
119431489
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
48 KB
Volume
138
Category
Article
ISSN
0016-5085

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Associations between variants in the ABC
โœ Alfreda Krupoves; David Mack; Ernest Seidman; Colette Deslandres; Devendra Amre ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 402 KB ๐Ÿ‘ 2 views

Background: Corticosteroids (CS) effectively induce remission in patients with moderate to severe Crohn's disease (CD). However, CS dependence in children is a significant clinical problem associated with numerous side effects. Identification of molecular markers of CS dependence is of paramount imp