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93 Rate of and Response to Dose Escalation in Pediatric Patients With Crohn's Disease From IMAgINE 1

✍ Scribed by Dubinsky, Marla; Rosh, Joel R.; Faubion, William A.; Kierkus, Jaroslaw; Ruemmele, Frank; Hyams, Jeffrey S.; Eichner, Samantha; Li, Yao; Lazar, Andreas; Thakkar, Roopal

Book ID: 122295007
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 332 KB
Volume: 146
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(14)60093-7

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## Background: To investigate the contribution of multidrug resistance 1 (MDR1) gene pharmacogenetics (G2677T/A and C3435T) to the efficacy of azathioprine in inducing remission in patients with Crohn's disease (CD). ## Methods: A cohort of 327 unrelated Spanish patients with CD recruited from