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9239 Polymorphisms of genes MDR1 and MTHRF in children with acute leukemia

โœ Scribed by Savitskaya, T.; Lipay, N.; Krivko, M.; Petina, O.; Kokarava, M.

Book ID
122713333
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
68 KB
Volume
7
Category
Article
ISSN
1359-6349

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The aim of this study is to determine whether the polymorphisms of the MDR1 gene are associated with the development of childhood acute lymphoblastic leukemia (ALL). The MDR1 gene polymorphisms, -2352 G>A, -934A>G, -692T>C (5' regulatory region) and 3435C>T (exon 26), were examined in 157 ALL patien