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9-cis-Retinoic Acid Decreases the Level of Its Cognate Receptor, Retinoid X Receptor, through Acceleration of the Turnover

✍ Scribed by Yoshio Nomura; Takashi Nagaya; Yoshitaka Hayashi; Fukushi Kambe; Hisao Seo

Book ID
115584073
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
181 KB
Volume
260
Category
Article
ISSN
0006-291X

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## Abstract Abstract vitamin D receptor (VDR) and retinoid X receptor (RXR) heterodimerize to mediate the genomic actions of 1Ξ±,25‐dihydroxyvitamin D~3~ (1Ξ±,25(OH)~2~D~3~, calcitriol), the biologically active form of vitamin D~3~. In this study, we show that 9‐__cis__ retinoic acid (9‐cisRA), the l